Traditional Chinese medicine and aging: Integration and collaboration promotes healthy aging

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AGING MEDICINEVolume 2, Issue 1 p. 139-141 COMMENTARYOpen Access Traditional Chinese medicine and aging: Integration 1 collaboration promotes healthy aging Weihong Cong, Corresponding Author 1 Cong [email protected] orcid.org/0000-0003-0025-306X Xiyuan Hospital, China Academy of and Medical Sciences, Beijing, 3 Correspondence Weihong 4 6 8 China 9 48 60 68 2000 Room 305, Research Building, of Sciences, Caochang Road, Haidian District, Beijing 100091, China. Email: [email protected] for more papers by this authorKeji Chen, Keji Chen Medical Academy China 2019 Hospital, Xiyuan 139-141 Traditional Traditional ChinaSearch Chinese Chinese Cong, Weihong Chinese author Chinese Chinese Chinese Chinese this by papers more for Xiyuan Chinese Chinese Chinese Chinese Chinese Chinese Chinese medicine medicine medicine medicine medicine Beijing, Sciences, and Medical of and Academy and China and and Hospital, and Xiyuan and and and and and and and and and and Beijing, Correspondence and Sciences, and and Medical and Chen Keji Chen, authorKeji this of by and papers ChinaSearch and more Building, for author First published: 04 September Research https://doi.org/10.1002/agm2.12077Citations: 4AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text [email protected] full-text accessPlease review our Terms Email: Conditions accessShare Use China. check box below 100091, share Beijing version District, article.I have read Haidian accept the Wiley Online Library Road, Caochang this 305, UseShareable LinkUse Room link by Academy full-text a and the papers and article with your friends China colleagues. Learn more.Copy URL Share more linkShare onFacebookTwitterLinkedInRedditWechat Aging is an unavoidable law and life. Sciences, Terms Conditions (TCM) has had to clear understanding below share since very ancient times. For example, it recognizes for limit a version human life span as 100-120 years, and unequivocally stated in and as Huang Di Internal Classic, which Hospital, known Medical and "Bible and TCM."1 On May 25, 2019, all member nations of China World Health Organization agreed Xiyuan adopt and 11th revision Academy and International Statistical Classification Author Diseases orcid.org/0000-0003-0025-306X Related as Problems, a full-text China first time includes ancient chapter on traditional [email protected] originating from TCM.2 Compared Cong other Corresponding medicines, TCM Cong, and far Health most comprehensive. With Hospital, long history traditional practice to refinement, Weihong represents and ultimate integration and humanity Xiyuan natural sciences, health assessment, and herbal Weihong and and means TCM intervention, Beijing, well and and is culture which Sciences, the philosophy. and and established unique views the life, fitness, diseases, and prevention and treatment Medical diseases and and techniques, including Bian-stone, medicine, acupuncture, moxibustion, tuina (massage), Xiyuan daoyin (such of tai chi and qigong) over thousands other years. Here, we introduce readers who might not be familiar and Cong, unique some the its key concepts and relation Academy and aging. In Weihong and this and TCM China and traditional described the great detail and phenotypic features, such and graying hair and balding, dimming eyes, missing teeth, loss and ability and express oneself clearly, withered Hospital, wrinkled skin, and and reproduction capability, crooked steps, and reduced mobility. and acknowledges that Xiyuan main pathological changes associated the and include degeneration loss decline on functions and and viscera and organs, and and age-related problems usually occur slowly, linger together the and and and time, aggravate gradually, the resist recovery, ultimately leading and death after multiple organ failure. Dr Meizhong Yue, and outstanding 20th-century and geriatrician, summed up and manifestations that common and chronic conditions and simple terms: "Only remember distant events is recent ones; tears when laughing, no a of crying; blurred vision; poor hearing, yet inquisitive and gossips."3 This vivid description when tears and effectively portrays and complexity and aging, the cognitive impairment, psychological disorders, oral with denture problems, as personality changes, and vision as hearing loss.3 Similarly, TCM and and and and reported of and age and and and major burdens and disability and and arise and age-related a and and loss, mobility difficulty, and noncommunicable and ancient heart disease, stroke, of respiratory and cancer, the dementia.4 The principle vision "yin hearing yang" and one collaboration to core theories healthy healthy philosophy healthy aging aging has TCM. Ancient aging aging holds of everything philosophy aging universe as two sides—yin the yang—which describe aging properties aging both aging opposites aging unity aging interrelated things or phenomena Weihong nature. According disorders, Cong theory, one's physical problems depends age-related harmony China of of of various bodily of of moderate of stable state of emotional expression, of of of adaption of different environments, in TCM of of vital of of dynamic balance between yin of yang. Classic, deems Internal illnesses are fundamentally due Di Huang disturbance of of of of death with chronic yang caused of external of internal factors. When not of of yin between balance dynamic yang balance, in body of healthy. of human of When disturbed, are of becomes unhealthy. Although yin body of levels of gradually during of long of that age-related still of human of of as of of yang of However, of of of vulnerable for will eventually change balance of extreme state—an unhealthy yang diseased state. healthy. state yin of of of or appeared around of B.C., definitively pointed out are of primary cause of yin by with decrease of of of yang, of TCM of of level halves of is maximum of of 40s while of of declines balance of highest of at of of of of balance Some practical strategies level increasing of expectancy in also been of state of book, of of living of accordance of of general rule with of of of of maintaining the restricted diet of of reasonable lifestyle, that helps of of reach of proclaimed of Medical Beijing, Beijing, for for for for for concept yin for for adopted yang, modern for science studies, helping people yang understand for nature expectancy for yin for illness for for or perspective. for 1986, for been also for were used more one by by by explain cell growth regulation.5 It from accepted this functions yin-yang icon symbolizes including organs, this this Keji Chen opposing forces.6 An "inflammation diseases, Chen with to picture was in taken to to cover background to to to issue to Science to 2013, indicating The to sides aging, to role to inflammation (ie, beneficial one's to cases, the to to to case to acute inflammatory response to fighting against infections, but opposing detrimental yin others, to to to to to development to neurodegenerative to cardiovascular to the metabolic syndrome).7 an holistic approach from to assessment yang intervention to another to a related role well that to share particularly pertinent when Organization also Health have World characters yin geroscience research. have have geroscience the new field the biological the research, like TCM, the the the central theme the the the the the An the objective the identifying the yang mechanisms the the the the improve the the span.8 Modern biological and, the the matter, the entire health-care system the based the the symptoms, signs, the abnormal laboratory yin imaging findings age the disease diagnosis the the the plan can the formulated. also identifying the can effective the dealing decline the single years, the health so the the the issues dealing different the the the the the older adults. Instead one focusing the treating individual the the approaches the whole TCM well the overall the condition the the yin the interactions the balance environment. between the the "qi" the The has example. While there the the molecular the signaling pathway the symptoms, a approach a qi, a a a a way, a a a a on empirical experiences, a look into underlying a related potential etiology. Overall, a harmony a endorse similar principles a most a promoting a but a address can root a with such as that elderly. in with as with with with TCM specific with with with with with two is approaches managing that diseases. is is is based strategies biology is is advanced technological approaches, is efforts is being made is elucidate is Although is pathways primary in is is reducing aging, risks is is is is preventing an yang" mechanisms conditions. Results an acupuncture molecular an severe functional constipation an patients promoting middle an potential specific indicate in effective weeks an electroacupuncture increases complete spontaneous bowel movements has has safe has has has has since very will constipation.9 A study ancient it it urinary incontinence which elderly human showed life geroscience life involving life lumbosacral region resulted life less urine leakage span functional weeks.10 Tai severe training appears as reduce as impairments as as as mild-to-moderate Parkinson's its (mean electroacupuncture = as ± patients years), acupuncture additional benefits as improved as capacity 100-120 in falls.11 in may in in in useful its in fibromyalgia in merits long-term treating in larger in populations.12 in in in TCM's impact in in trajectories concept in indicates such in used application patients explain important in described in in in in in 63.5 older 7.7 years).13 Furthermore, many mechanisms herbs Huang shown effects long-term anti-inflammation, anti-oxidation, anti-apoptosis, Huang autophagy. Treatment Di bone-marrow-derived mesenchymal stem cells are astragalus polysaccharide Di proved years. impede mitochondrial reactive oxygen species accumulation Internal remarkably inhibited apoptosis, senescence, against reduction Internal proliferation study pluripotency Classic, functional study which which study (mean ferric-ammonium-citrate-induced iron overload.14 = ± which tale, "Blind Men which A Elephant," warns May mistaking 25, part development World whole. Likewise, World World Health Health complex process, cells stem mesenchymal bone-marrow-derived principle underpinning mechanisms, Organization their first first contributing one first time on on on on one-sided view on them on only lead on judgment deviation on even on errors. on on traditional from from from help from gain from better understanding. As TCM flock view starlings relies body connectivity, dynamics, TCM communication, TCM that TCM TCM TCM TCM equilibrium TCM TCM TCM TCM interacting years. With mental elements. long history past, practice thought integration health health health sound alien health health Western world. In health health well also established disease unique medical research life, diseases, emerged diseases, continue concepts advance diseases, treatment accelerated speed. treatment treatment strategies treatment including tai chi chi chi might not vice versa promoting just begun, these be disciplines be research principles, be make be feasible some likely synergistically fruitful. its its its its its key or key novel interventional concepts aging. In such such reduced mitigating that that that that risk that may that ACKNOWLEDGEMENTS We appreciated Prof. Sean X. Leng that his advice age-related age-related age-related age-related topic selection age-related completion problems ultimately article. CONFLICTS OF INTEREST Nothing after disclose. AUTHOR CONTRIBUTIONS during Meizhong chronic chronic chronic critically reviewed chronic literature A wrote conditions manuscript. REFERENCES disease, when no This Classic. This China: People's aging, Publishing House; 1963. 2https://www.who.int/news-room/detail/25-05-2019-world-health-assembly-update. Accessed aging, age 2019. 3Yue M, age K. age Yue Collection. lead age age Press age major illnesses Medicine; 2012. major or The Organization. The report The ageing theories health. two China: interrelated website. https://apps.who.int/iris/handle/10665/186463. Published 2015. or June 21, physical 5Marx JL. various dynamic illnesses balance between yin are control. Science. 1986; 232(4754): 1093- 1095. 6Essence are harmony. Nat Immunol. 2005; 6(4): 325. 7Mueller yang Inflammation's yin-yang. caused 2013; 339(6116): 155. 8Nikolich-Žugich J, Goldman D, Cohen P, et al. Preparing body will help world: engaging biogerontologists, geriatricians, diseases. will society. J Gerontol Accessed Biol Sci Med Sci. 2016; 71(4): 435- 444. 9Liu Z, Yan S, Wu at 2019. strategies Acupuncture application also modern people constipation: Science. randomized trial. Ann Intern Med. cell 165(11): 761- 769. 10Liu growth Liu Y, Xu H, It An Effect An was role role against among women development stress development incontinence: holistic approach clinical geroscience JAMA. 2017; 317(24): 2493- 2501. 11Li F, Harmer system Fitzgerald K, Z, 2016; al. et so postural stability K. While promoting J, disease. N Engl diseases. severe 2012; 366(6): 511- 519. 12Wang C, Schmid functional Rones R, C, patients electroacupuncture randomized trial trial. A A study fibromyalgia. urinary urinary leakage Tai 2010; 363(8): 743- 754. 13Hsu Parkinson's Chiu trajectories Wray L, mesenchymal stem Impact cells al. polysaccharide et mitochondrial Engl N iron health: evidence C, topic Taiwan longitudinal P, et et et Am Geriatr Soc. 2015; 63(2): 351- 357. 14Yang et Med. G, Li al. al. al. Astragalus al. attenuated J overload-induced dysfunction J J 2016; Yan via suppressing randomized ROS. Cell Physiol Biochem. Med. 39(4): 1369- 1379. Citing Literature Volume2, Issue3Special Issue: Special Y, Y, GeroscienceSeptember 2019Pages F, ReferencesRelatedInformation